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Beilstein J. Org. Chem. 2023, 19, 107–114, doi:10.3762/bjoc.19.11
Graphical Abstract
Scheme 1: Synthesis of ether triazolopyrazine derivatives 4–9.
Scheme 2: Synthesis of fluorinated triazolopyrazine compounds (10–18) via Diversinate™ chemistry.
Figure 1: Key HMBC, COSY and ROESY correlations, and ORTEP drawing of 18.
Beilstein J. Org. Chem. 2022, 18, 1544–1552, doi:10.3762/bjoc.18.164
Figure 1: UHPLC–UV chromatogram (254 nm) of the CH2Cl2/MeOH extract of Ianthella basta (NB6021519); retention...
Figure 2: Chemical structures of 5-debromopurealidin H (1) and ianthesine E (2).
Figure 3: Key COSY, HMBC and ROESY correlations for 5-debromopurealidin H (1).
Figure 4: Chemical structures of the NatureBank bromotyrosine derivatives: psammaplysins F (3) and H (4), bas...
Figure 5: Dose-response assessment of in vitro activity of compounds 1–9 against exsheathed third-stage larva...